The role of Rad51 in safeguarding mitochondrial activity during the meiotic cell cycle in mammalian oocytes

Rad51 is a conserved eukaryotic protein that mediates the homologous recombination repair of DNA double-strand breaks that occur during mitosis and meiosis. In addition, Rad51 promotes mitochondrial DNA synthesis when replication stress is increased. Rad51 also regulates cell cycle progression by pr...

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Udgivet i:Sci Rep
Main Authors: Kim, Kyeoung-Hwa, Park, Ji-Hoon, Kim, Eun-Young, Ko, Jung-Jae, Park, Kyung-Soon, Lee, Kyung-Ah
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039699/
https://ncbi.nlm.nih.gov/pubmed/27677401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34110
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