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Persistence of fan-shaped keratocytes is a matrix-rigidity-dependent mechanism that requires α(5)β(1) integrin engagement

Despite the importance of matrix rigidity on cell functions, many aspects of the mechanosensing process in highly migratory cells remain elusive. Here, we studied the migration of highly motile keratocytes on culture substrates with similar biochemical properties and rigidities spanning the range be...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Riaz, Maryam, Versaevel, Marie, Mohammed, Danahe, Glinel, Karine, Gabriele, Sylvain
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039689/
https://ncbi.nlm.nih.gov/pubmed/27678055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34141
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