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Cross-talk between Human Papillomavirus Oncoproteins and Hedgehog Signaling Synergistically Promotes Stemness in Cervical Cancer Cells

Viral oncoproteins E6/E7 play key oncogenic role in human papillomavirus (HPV)-mediated cervical carcinogenesis in conjunction with aberrant activation of cellular signaling events. GLI-signaling has been implicated in metastasis and tumor recurrence of cervical cancer. However, the interaction of G...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vishnoi, Kanchan, Mahata, Sutapa, Tyagi, Abhishek, Pandey, Arvind, Verma, Gaurav, Jadli, Mohit, Singh, Tejveer, Singh, Sukh Mahendra, Bharti, Alok C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039669/
https://ncbi.nlm.nih.gov/pubmed/27678330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34377
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