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Depletion of primary cilia from mature dentate granule cells impairs hippocampus-dependent contextual memory

The primary cilium, a sensory organelle, regulates cell proliferation and neuronal development of dentate granule cells in the hippocampus. However, its role in the function of mature dentate granule cells remains unknown. Here we specifically depleted and disrupted ciliary proteins IFT20 and Kif3A...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Rhee, Soyoung, Kirschen, Gregory W., Gu, Yan, Ge, Shaoyu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039642/
https://ncbi.nlm.nih.gov/pubmed/27678193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34370
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