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Repurposing clinically approved cephalosporins for tuberculosis therapy

While modern cephalosporins developed for broad spectrum antibacterial activities have never been pursued for tuberculosis (TB) therapy, we identified first generation cephalosporins having clinically relevant inhibitory concentrations, both alone and in synergistic drug combinations. Common chemica...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Ramón-García, Santiago, González del Río, Rubén, Villarejo, Angel Santos, Sweet, Gaye D., Cunningham, Fraser, Barros, David, Ballell, Lluís, Mendoza-Losana, Alfonso, Ferrer-Bazaga, Santiago, Thompson, Charles J.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039641/
https://ncbi.nlm.nih.gov/pubmed/27678056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34293
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