Repurposing clinically approved cephalosporins for tuberculosis therapy

While modern cephalosporins developed for broad spectrum antibacterial activities have never been pursued for tuberculosis (TB) therapy, we identified first generation cephalosporins having clinically relevant inhibitory concentrations, both alone and in synergistic drug combinations. Common chemica...

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Pubblicato in:Sci Rep
Autori principali: Ramón-García, Santiago, González del Río, Rubén, Villarejo, Angel Santos, Sweet, Gaye D., Cunningham, Fraser, Barros, David, Ballell, Lluís, Mendoza-Losana, Alfonso, Ferrer-Bazaga, Santiago, Thompson, Charles J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039641/
https://ncbi.nlm.nih.gov/pubmed/27678056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34293
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