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Mechanistic and Structural Studies of Protein-Only RNase P Compared to Ribonucleoproteins Reveal the Two Faces of the Same Enzymatic Activity

RNase P, the essential activity that performs the 5′ maturation of tRNA precursors, can be achieved either by ribonucleoproteins containing a ribozyme present in the three domains of life or by protein-only enzymes called protein-only RNase P (PRORP) that occur in eukaryote nuclei and organelles. A...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Schelcher, Cédric, Sauter, Claude, Giegé, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039416/
https://ncbi.nlm.nih.gov/pubmed/27348014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom6030030
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