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Mechanistic and Structural Studies of Protein-Only RNase P Compared to Ribonucleoproteins Reveal the Two Faces of the Same Enzymatic Activity

RNase P, the essential activity that performs the 5′ maturation of tRNA precursors, can be achieved either by ribonucleoproteins containing a ribozyme present in the three domains of life or by protein-only enzymes called protein-only RNase P (PRORP) that occur in eukaryote nuclei and organelles. A...

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Publicado en:Biomolecules
Autores principales: Schelcher, Cédric, Sauter, Claude, Giegé, Philippe
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039416/
https://ncbi.nlm.nih.gov/pubmed/27348014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom6030030
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