Detecting Circulating Tumor DNA in Hepatocellular Carcinoma Patients Using Droplet Digital PCR Is Feasible and Reflects Intratumoral Heterogeneity

Purpose: Circulating tumor DNA (ctDNA) is increasingly recognized as liquid biopsy to profile tumor genome. Droplet digital PCR (ddPCR) is a highly sensitive and easily operable platform for mutant detection. Here, we tried to detect ctDNA in hepatocellular carcinoma (HCC) patients using ddPCR. Meth...

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Опубликовано в: :J Cancer
Главные авторы: Huang, Ao, Zhang, Xin, Zhou, Shao-Lai, Cao, Ya, Huang, Xiao-Wu, Fan, Jia, Yang, Xin-Rong, Zhou, Jian
Формат: Artigo
Язык:Inglês
Опубликовано: Ivyspring International Publisher 2016
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039376/
https://ncbi.nlm.nih.gov/pubmed/27698932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.15823
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