Immunomodulatory Effects of 1,25-Dihydroxyvitamin D(3) on Dendritic Cells Promote Induction of T Cell Hyporesponsiveness to Myelin-Derived Antigens

While emerging evidence indicates that dendritic cells (DC) play a central role in the pathogenesis of multiple sclerosis (MS), their modulation with immunoregulatory agents provides prospect as disease-modifying therapy. Our observations reveal that 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) trea...

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Dettagli Bibliografici
Pubblicato in:J Immunol Res
Autori principali: Lee, Wai-Ping, Willekens, Barbara, Cras, Patrick, Goossens, Herman, Martínez-Cáceres, Eva, Berneman, Zwi N., Cools, Nathalie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039280/
https://ncbi.nlm.nih.gov/pubmed/27703987
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5392623
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