Chemogenetic Activation of an Extinction Neural Circuit Reduces Cue-Induced Reinstatement of Cocaine Seeking

The ventromedial prefrontal cortex (vmPFC) has been shown to negatively regulate cocaine-seeking behavior, but the precise conditions by which vmPFC activity can be exploited to reduce cocaine relapse are currently unknown. We used viral-mediated gene transfer of designer receptors (DREADDs) to acti...

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Udgivet i:J Neurosci
Main Authors: Augur, Isabel F., Wyckoff, Andrew R., Aston-Jones, Gary, Kalivas, Peter W., Peters, Jamie
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2016
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039261/
https://ncbi.nlm.nih.gov/pubmed/27683912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0773-16.2016
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