Hypocretin/Orexin Peptides Alter Spike Encoding by Serotonergic Dorsal Raphe Neurons through Two Distinct Mechanisms That Increase the Late Afterhyperpolarization

Orexins (hypocretins) are neuropeptides that regulate multiple homeostatic processes, including reward and arousal, in part by exciting serotonergic dorsal raphe neurons, the major source of forebrain serotonin. Here, using mouse brain slices, we found that, instead of simply depolarizing these neur...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Ishibashi, Masaru, Gumenchuk, Iryna, Miyazaki, Kenichi, Inoue, Takafumi, Ross, William N., Leonard, Christopher S.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039256/
https://ncbi.nlm.nih.gov/pubmed/27683906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0635-16.2016
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