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Combining Chemometric Models with Adsorption Isotherm Measurements to Study Omeprazole in RP-LC

The adsorption of the proton-pump inhibitor omeprazole was investigated using RP-LC with chemometric models combined with adsorption isotherm modelling to study the effect of pH and type of organic modifier (i.e., acetonitrile or methanol). The chemometric approach revealed that omeprazole was taili...

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Bibliographische Detailangaben
Veröffentlicht in:Chromatographia
Hauptverfasser: Åsberg, Dennis, Leśko, Marek, Samuelsson, Jörgen, Karlsson, Anders, Kaczmarski, Krzysztof, Fornstedt, Torgny
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039227/
https://ncbi.nlm.nih.gov/pubmed/27738352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10337-016-3151-8
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