Combining Chemometric Models with Adsorption Isotherm Measurements to Study Omeprazole in RP-LC

The adsorption of the proton-pump inhibitor omeprazole was investigated using RP-LC with chemometric models combined with adsorption isotherm modelling to study the effect of pH and type of organic modifier (i.e., acetonitrile or methanol). The chemometric approach revealed that omeprazole was taili...

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Dettagli Bibliografici
Pubblicato in:Chromatographia
Autori principali: Åsberg, Dennis, Leśko, Marek, Samuelsson, Jörgen, Karlsson, Anders, Kaczmarski, Krzysztof, Fornstedt, Torgny
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Berlin Heidelberg 2016
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Original
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039227/
https://ncbi.nlm.nih.gov/pubmed/27738352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10337-016-3151-8
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