Combining Chemometric Models with Adsorption Isotherm Measurements to Study Omeprazole in RP-LC

The adsorption of the proton-pump inhibitor omeprazole was investigated using RP-LC with chemometric models combined with adsorption isotherm modelling to study the effect of pH and type of organic modifier (i.e., acetonitrile or methanol). The chemometric approach revealed that omeprazole was taili...

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Bibliographic Details
Published in:Chromatographia
Main Authors: Åsberg, Dennis, Leśko, Marek, Samuelsson, Jörgen, Karlsson, Anders, Kaczmarski, Krzysztof, Fornstedt, Torgny
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2016
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Original
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039227/
https://ncbi.nlm.nih.gov/pubmed/27738352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10337-016-3151-8
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