Proteomics of Human Dendritic Cell Subsets Reveals Subset-Specific Surface Markers and Differential Inflammasome Function

Dendritic cells (DCs) play a key role in orchestrating adaptive immune responses. In human blood, three distinct subsets exist: plasmacytoid DCs (pDCs) and BDCA3+ and CD1c+ myeloid DCs. In addition, a DC-like CD16+ monocyte has been reported. Although RNA-expression profiles have been previously com...

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Publicat a:Cell Rep
Autors principals: Worah, Kuntal, Mathan, Till S.M., Vu Manh, Thien Phong, Keerthikumar, Shivakumar, Schreibelt, Gerty, Tel, Jurjen, Duiveman-de Boer, Tjitske, Sköld, Annette E., van Spriel, Annemiek B., de Vries, I. Jolanda M., Huynen, Martijn A., Wessels, Hans J., Gloerich, Jolein, Dalod, Marc, Lasonder, Edwin, Figdor, Carl G., Buschow, Sonja I.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039226/
https://ncbi.nlm.nih.gov/pubmed/27626665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.08.023
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