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Measuring relative utilization of aerobic glycolysis in breast cancer cells by positional isotopic discrimination

The ability of cancer cells to produce lactate through aerobic glycolysis is a hallmark of cancer. In this study, we established a positional isotopic labeling and LC-MS-based method that can specifically measure the conversion of glucose to lactate in glycolysis. We show that the rate of aerobic gl...

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Bibliografski detalji
Izdano u:FEBS Lett
Glavni autori: Yang, Da-Qing, Freund, Dana M., Harris, Benjamin RE, Wang, Defeng, Cleary, Margot P., Hegeman, Adrian D.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039094/
https://ncbi.nlm.nih.gov/pubmed/27531463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12360
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