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Measuring relative utilization of aerobic glycolysis in breast cancer cells by positional isotopic discrimination
The ability of cancer cells to produce lactate through aerobic glycolysis is a hallmark of cancer. In this study, we established a positional isotopic labeling and LC-MS-based method that can specifically measure the conversion of glucose to lactate in glycolysis. We show that the rate of aerobic gl...
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Izdano u: | FEBS Lett |
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Glavni autori: | , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2016
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Teme: | |
Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5039094/ https://ncbi.nlm.nih.gov/pubmed/27531463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.12360 |
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