Regulated assembly of a supramolecular centrosome scaffold in vitro

The centrosome organizes microtubule arrays within animal cells and comprises two centrioles surrounded by an amorphous protein mass called the pericentriolar material (PCM). Despite the importance of centrosomes as microtubule-organizing centers, the mechanism and regulation of PCM assembly are not...

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Publicado en:Science
Autores principales: Woodruff, Jeffrey B., Wueseke, Oliver, Viscardi, Valeria, Mahamid, Julia, Ochoa, Stacy D., Bunkenborg, Jakob, Widlund, Per O., Pozniakovsky, Andrei, Zanin, Esther, Bahmanyar, Shirin, Zinke, Andrea, Hong, Sun Hae, Decker, Marcus, Baumeister, Wolfgang, Andersen, Jens S., Oegema, Karen, Hyman, Anthony A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039038/
https://ncbi.nlm.nih.gov/pubmed/25977552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaa3923
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