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Shikonin inhibits inflammation and chondrocyte apoptosis by regulation of the PI3K/Akt signaling pathway in a rat model of osteoarthritis

Shikonin has previously been shown to have antitumor, anti-inflammatory, antiviral and extensive pharmacological effects. The aim of the present study was to explore whether the protective effect of shikonin is mediated via the inhibition of inflammation and chondrocyte apoptosis, and to elucidate t...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Fu, Daijie, Shang, Xifu, Ni, Zhe, Shi, Guoguang
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038895/
https://ncbi.nlm.nih.gov/pubmed/27703516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2016.3642
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