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17AAG-induced internalisation of HER2-specific Affibody molecules

The geldanamycin derivative 17-allylamino-17-demethoxygeldanamycin (17-AAG) is known to induce internalisation and degradation of the otherwise internalisation-resistant human epidermal growth factor receptor 2 (HER2) receptor. In the present study, 17-AAG was used to increase internalisation of the...

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Pubblicato in:Oncol Lett
Autori principali: Göstring, Lovisa, Lindegren, Sture, Gedda, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038849/
https://ncbi.nlm.nih.gov/pubmed/27698830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2016.4990
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