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Diazepam-binding inhibitor (DBI)-processing products, acting at the mitochondrial DBI receptor, mediate adrenocorticotropic hormone-induced steroidogenesis in rat adrenal gland.

Diazepam-binding inhibitor (DBI) is a 9-kDa polypeptide that colocalizes in glial, adrenocortical, and Leydig cells with the mitochondrial DBI receptor (MDR). By binding with high affinity to the MDR, DBI and one of its processing products--DBI-(17-50)--regulate pregnenolone synthesis and have been...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Cavallaro, S, Korneyev, A, Guidotti, A, Costa, E
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50388/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1279686/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.10598
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