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Fullerene Derivatives Strongly Inhibit HIV-1 Replication by Affecting Virus Maturation without Impairing Protease Activity

Three compounds (1, 2, and 3) previously reported to inhibit HIV-1 replication and/or in vitro activity of reverse transcriptase were studied, but only fullerene derivatives 1 and 2 showed strong antiviral activity on the replication of HIV-1 in human CD4(+) T cells. However, these compounds did not...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Martinez, Zachary S., Castro, Edison, Seong, Chang-Soo, Cerón, Maira R., Echegoyen, Luis, Llano, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038267/
https://ncbi.nlm.nih.gov/pubmed/27431232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00341-16
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