A crystallographic study of human NONO (p54(nrb)): overcoming pathological problems with purification, data collection and noncrystallographic symmetry

Non-POU domain-containing octamer-binding protein (NONO, a.k.a. p54(nrb)) is a central player in nuclear gene regulation with rapidly emerging medical significance. NONO is a member of the highly conserved Drosophila behaviour/human splicing (DBHS) protein family, a dynamic family of obligatory dime...

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Bibliographic Details
Published in:Acta Crystallogr D Struct Biol
Main Authors: Knott, Gavin J., Panjikar, Santosh, Thorn, Andrea, Fox, Archa H., Conte, Maria R., Lee, Mihwa, Bond, Charles S.
Format: Artigo
Language:Inglês
Published: International Union of Crystallography 2016
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038197/
https://ncbi.nlm.nih.gov/pubmed/27303796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2059798316005830
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