Structural Basis for Recombinatorial Permissiveness in the Generation of Anaplasma marginale Msp2 Antigenic Variants

Sequential expression of outer membrane protein antigenic variants is an evolutionarily convergent mechanism used by bacterial pathogens to escape host immune clearance and establish persistent infection. Variants must be sufficiently structurally distinct to escape existing immune effectors yet ret...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Graça, Telmo, Silva, Marta G., Kostyukova, Alla S., Palmer, Guy H.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2016
Subjects:
Bacterial Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038088/
https://ncbi.nlm.nih.gov/pubmed/27400719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00391-16
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