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Structural Basis for Recombinatorial Permissiveness in the Generation of Anaplasma marginale Msp2 Antigenic Variants

Sequential expression of outer membrane protein antigenic variants is an evolutionarily convergent mechanism used by bacterial pathogens to escape host immune clearance and establish persistent infection. Variants must be sufficiently structurally distinct to escape existing immune effectors yet ret...

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Vydáno v:Infect Immun
Hlavní autoři: Graça, Telmo, Silva, Marta G., Kostyukova, Alla S., Palmer, Guy H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038088/
https://ncbi.nlm.nih.gov/pubmed/27400719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00391-16
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