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Protein expression of targets of the FMRP regulon is altered in brains of subjects with schizophrenia and mood disorders
Fragile X mental retardation protein (FMRP) is an RNA binding protein with 842 target mRNAs in mammalian brain. Silencing of the fragile X mental retardation 1 (FMR1) gene leads to loss of expression of FMRP and upregulated metabotropic glutamate receptor 5 (mGluR5) signaling resulting in the multip...
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| Publicat a: | Schizophr Res |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5037955/ https://ncbi.nlm.nih.gov/pubmed/25956630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2015.04.012 |
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