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The T cell cometh: interplay between adaptive immunity and cytokine networks in rheumatoid arthritis

The etiology of autoimmunity in humans remains poorly defined, and animal models provide a unique opportunity to study potential autoimmune mechanisms. A novel model of autoimmune inflammatory arthritis results from a point mutation in the ζ-associated–protein of 70 kDa (ZAP-70), which causes abnorm...

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Detalhes bibliográficos
Autor principal: Firestein, Gary S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC503778/
https://ncbi.nlm.nih.gov/pubmed/15314683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200422651
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