Genome-wide association and replication study of anti-tuberculosis drugs-induced liver toxicity

BACKGROUND: Drug-induced liver injury (DILI) is a well-recognized adverse event of anti tuberculosis drugs (ATD) possibly associated with genetic variations. The objective of this study was to perform genome-wide association study (GWAS) to identify genetic variants associated with the risk for ATD...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Petros, Zelalem, Lee, Ming-Ta Michael, Takahashi, Atsushi, Zhang, Yanfei, Yimer, Getnet, Habtewold, Abiy, Amogne, Wondwossen, Aderaye, Getachew, Schuppe-Koistinen, Ina, Mushiroda, Taisei, Makonnen, Eyasu, Kubo, Michiaki, Aklillu, Eleni
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037629/
https://ncbi.nlm.nih.gov/pubmed/27671213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-3078-3
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