The frequency and skewed T-cell receptor beta-chain variable patterns of peripheral CD4(+)CD25(+) regulatory T-cells are associated with hepatitis B e antigen seroconversion of chronic hepatitis B patients during antiviral treatment

The frequency and T-cell receptor beta-chain variable (TCRBV) patterns of peripheral CD4(+)CD25(+) regulatory T-cells (Tregs) are ambiguously altered in chronic hepatitis B (CHB) patients following tenofovir disoproxil fumarate (TDF) treatment. Moreover, the clinical significance of these parameters...

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Bibliographic Details
Published in:Cell Mol Immunol
Main Authors: Yang, Jiezuan, Sheng, Guoping, Xiao, Dangsheng, Shi, Haiyan, Wu, Wei, Lu, Haifeng, Cao, Hongcui, Li, Lanjuan
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037272/
https://ncbi.nlm.nih.gov/pubmed/26899927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.100
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