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Significant loss of sensitivity and specificity in the taxonomic classification occurs when short 16S rRNA gene sequences are used

The classification performance of Kraken was evaluated in terms of sensitivity and specificity when using short and long 16S rRNA sequences. A total of 440,738 sequences from bacteria with complete taxonomic classifications were downloaded from the high quality ribosomal RNA database SILVA. Amplicon...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Martínez-Porchas, Marcel, Villalpando-Canchola, Enrique, Vargas-Albores, Francisco
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037269/
https://ncbi.nlm.nih.gov/pubmed/27699286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2016.e00170
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