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Modeling a synthetic multicellular clock: Repressilators coupled by quorum sensing

Diverse biochemical rhythms are generated by thousands of cellular oscillators that somehow manage to operate synchronously. In fields ranging from circadian biology to endocrinology, it remains an exciting challenge to understand how collective rhythms emerge in multicellular structures. Using math...

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Autors principals: Garcia-Ojalvo, Jordi, Elowitz, Michael B., Strogatz, Steven H.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC503725/
https://ncbi.nlm.nih.gov/pubmed/15256602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307095101
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