Effects of N-acetylcysteine (NAC) supplementation in resuscitation fluids on renal microcirculatory oxygenation, inflammation, and function in a rat model of endotoxemia

BACKGROUND: Modulation of inflammation and oxidative stress appears to limit sepsis-induced damage in experimental models. The kidney is one of the most sensitive organs to injury during septic shock. In this study, we evaluated the effect of N-acetylcysteine (NAC) administration in conjunction with...

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Dettagli Bibliografici
Pubblicato in:Intensive Care Med Exp
Autori principali: Ergin, Bulent, Guerci, Philippe, Zafrani, Lara, Nocken, Frank, Kandil, Asli, Gurel-Gurevin, Ebru, Demirci-Tansel, Cihan, Ince, Can
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer International Publishing 2016
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037099/
https://ncbi.nlm.nih.gov/pubmed/27671340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40635-016-0106-1
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