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Novel molecular insights into the critical role of sulfatide in myelin maintenance/function

Cerebroside sulfotransferase (CST) catalyzes the production of sulfatide, a major class of myelin-specific lipids. CST knockout (CST(−/−)) mice in which sulfatide is completely depleted are born healthy, but display myelin abnormalities and progressive tremors starting at 4–6 weeks of age. Although...

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Dettagli Bibliografici
Pubblicato in:J Neurochem
Autori principali: Palavicini, Juan Pablo, Wang, Chunyan, Chen, Linyuan, Ahmar, Sareen, Higuera, Juan Diego, Dupree, Jeffrey L., Han, Xianlin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5037006/
https://ncbi.nlm.nih.gov/pubmed/27417284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.13738
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