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Differential effects of hydrocortisone, prednisone, and dexamethasone on hormonal and pharmacokinetic profiles: a pilot study in children with congenital adrenal hyperplasia

BACKGROUND: Little is known about the comparative effects of different glucocorticoids on the adrenal and growth hormone (GH) axes in children with congenital adrenal hyperplasia (CAH). We sought to compare the effects of hydrocortisone (HC), prednisone (PDN), and dexamethasone (DEX) in children wit...

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Veröffentlicht in:Int J Pediatr Endocrinol
Hauptverfasser: Nebesio, Todd D., Renbarger, Jamie L., Nabhan, Zeina M., Ross, Sydney E., Slaven, James E., Li, Lang, Walvoord, Emily C., Eugster, Erica A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036261/
https://ncbi.nlm.nih.gov/pubmed/27688786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13633-016-0035-5
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