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GDF11 decreases bone mass by stimulating osteoclastogenesis and inhibiting osteoblast differentiation
Osteoporosis is an age-related disease that affects millions of people. Growth differentiation factor 11 (GDF11) is a secreted member of the transforming growth factor beta (TGF-β) superfamily. Deletion of Gdf11 has been shown to result in a skeletal anterior–posterior patterning disorder. Here we s...
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| 出版年: | Nat Commun |
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| 主要な著者: | , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5036163/ https://ncbi.nlm.nih.gov/pubmed/27653144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12794 |
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