A polyvalent inactivated rhinovirus vaccine is broadly immunogenic in rhesus macaques

As the predominant aetiological agent of the common cold, human rhinovirus (HRV) is the leading cause of human infectious disease. Early studies showed that a monovalent formalin-inactivated HRV vaccine can be protective, and virus-neutralizing antibodies (nAb) correlated with protection. However, c...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Lee, Sujin, Nguyen, Minh Trang, Currier, Michael G., Jenkins, Joe B., Strobert, Elizabeth A., Kajon, Adriana E., Madan-Lala, Ranjna, Bochkov, Yury A., Gern, James E., Roy, Krishnendu, Lu, Xiaoyan, Erdman, Dean D., Spearman, Paul, Moore, Martin L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036149/
https://ncbi.nlm.nih.gov/pubmed/27653379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12838
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