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CD4 cell count and CD4/CD8 ratio increase during rituximab maintenance in granulomatosis with polyangiitis patients

INTRODUCTION: Rituximab (RTX) is a B cell-depleting agent approved for the treatment of granulomatosis with polyangiitis (GPA). RTX reduces antibody producing precursor plasma cells and inhibits B and T cells interaction. Infections related to T cell immunodeficiency are not infrequent during RTX tr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PeerJ
Prif Awduron: Besada, Emilio, Nossent, Johannes C.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: PeerJ Inc. 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036106/
https://ncbi.nlm.nih.gov/pubmed/27688979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2487
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