Short-term MRI measurements as predictors of EDSS progression in relapsing-remitting multiple sclerosis: grey matter atrophy but not lesions are predictive in a real-life setting

BACKGROUND: Magnetic resonance imaging (MRI) is the best biomarker of inflammatory disease activity in relapsing remitting Multiple Sclerosis (RRMS) so far but the association with disability is weak. Appearance of new MRI-lesions is used to evaluate response to immunotherapies in individual patient...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PeerJ
Hauptverfasser: von Gumberz, Johanna, Mahmoudi, Mina, Young, Kim, Schippling, Sven, Martin, Roland, Heesen, Christoph, Siemonsen, Susanne, Stellmann, Jan-Patrick
Format: Artigo
Sprache:Inglês
Veröffentlicht: PeerJ Inc. 2016
Schlagworte:
Neurology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036070/
https://ncbi.nlm.nih.gov/pubmed/27688965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7717/peerj.2442
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