Automated Enrichment, Transduction, and Expansion of Clinical-Scale CD62L(+) T Cells for Manufacturing of Gene Therapy Medicinal Products

Multiple clinical studies have demonstrated that adaptive immunotherapy using redirected T cells against advanced cancer has led to promising results with improved patient survival. The continuously increasing interest in those advanced gene therapy medicinal products (GTMPs) leads to a manufacturin...

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Pubblicato in:Hum Gene Ther
Autori principali: Priesner, Christoph, Aleksandrova, Krasimira, Esser, Ruth, Mockel-Tenbrinck, Nadine, Leise, Jana, Drechsel, Katharina, Marburger, Michael, Quaiser, Andrea, Goudeva, Lilia, Arseniev, Lubomir, Kaiser, Andrew D., Glienke, Wolfgang, Koehl, Ulrike
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2016
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035932/
https://ncbi.nlm.nih.gov/pubmed/27562135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2016.091
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