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Point mutations in the major outer membrane protein drive hypervirulence of a rapidly expanding clone of Campylobacter jejuni

Infections due to clonal expansion of highly virulent bacterial strains are clear and present threats to human and animal health. Association of genetic changes with disease is now a routine, but identification of causative mutations that enable disease remains difficult. Campylobacter jejuni is an...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Wu, Zuowei, Periaswamy, Balamurugan, Sahin, Orhan, Yaeger, Michael, Plummer, Paul, Zhai, Weiwei, Shen, Zhangqi, Dai, Lei, Chen, Swaine L., Zhang, Qijing
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035848/
https://ncbi.nlm.nih.gov/pubmed/27601641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605869113
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