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Point mutations in the major outer membrane protein drive hypervirulence of a rapidly expanding clone of Campylobacter jejuni

Infections due to clonal expansion of highly virulent bacterial strains are clear and present threats to human and animal health. Association of genetic changes with disease is now a routine, but identification of causative mutations that enable disease remains difficult. Campylobacter jejuni is an...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wu, Zuowei, Periaswamy, Balamurugan, Sahin, Orhan, Yaeger, Michael, Plummer, Paul, Zhai, Weiwei, Shen, Zhangqi, Dai, Lei, Chen, Swaine L., Zhang, Qijing
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035848/
https://ncbi.nlm.nih.gov/pubmed/27601641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1605869113
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