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Asymmetric Synthesis of Dipropionate Derivatives through Catalytic Hydrogenation of Enantioenriched E-Ketene Heterodimers

A highly diastereoselective approach to dipropionate derivatives through Pd/C-catalyzed hydrogenation of enantioenriched E-ketene heterodimers is described. Catalytic hydrogenation of the E-isomer of ketene heterodimer β-lactones (12 examples) provides access to syn,anti-β-lactones (dipropionate der...

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Detalhes bibliográficos
Publicado no:Synthesis (Stuttg)
Main Authors: Chen, Shi, Mondal, Mukulesh, Ibrahim, Ahmad A., Wheeler, Kraig A., Kerrigan, Nessan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035679/
https://ncbi.nlm.nih.gov/pubmed/27681860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0035-1561958
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