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Anticipatory UPR Activation: A Protective Pathway and Target in Cancer
The endoplasmic reticulum (EnR) stress sensor, the unfolded protein response (UPR), plays a key role in regulating intracellular protein homeostasis. The extensively studied reactive mode of UPR activation is characterized by unfolded protein, or other EnR stress, triggering UPR activation. Here we...
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| Publicado no: | Trends Endocrinol Metab |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5035594/ https://ncbi.nlm.nih.gov/pubmed/27354311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tem.2016.06.002 |
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