Racial Disparities in the Risk of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis as Urate-Lowering Drug Adverse Events in the US

OBJECTIVES: HLA-B*5801 allele carriage (a strong determinant of allopurinol hypersensitivity syndrome) varies substantially among races, which may lead to racial disparities in the risk of Stevens-Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) in the context of urate-lowering drug adver...

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Publicado en:Semin Arthritis Rheum
Autores principales: Lu, Na, Rai, Sharan K., Terkeltaub, Robert, Kim, Seoyoung C., Menendez, Mariano E., Choi, Hyon K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035554/
https://ncbi.nlm.nih.gov/pubmed/27217070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semarthrit.2016.03.014
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