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Age-dependent modulation of vascular niches for haematopoietic stem cells

Blood vessels define local microenvironments in the skeletal system, play crucial roles in osteogenesis and provide niches for haematopoietic stem cells1–6. The properties of niche-forming vessels and their changes in the ageing organism remain incompletely understood. Here, we show that Notch signa...

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Bibliografiske detaljer
Udgivet i:Nature
Main Authors: Kusumbe, Anjali P., Ramasamy, Saravana K., Itkin, Tomer, Andaloussi Mäe, Maarja, Langen, Urs H., Betsholtz, Christer, Lapidot, Tsvee, Adams, Ralf H.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035541/
https://ncbi.nlm.nih.gov/pubmed/27074508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17638
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