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Identification of control targets in Boolean molecular network models via computational algebra

BACKGROUND: Many problems in biomedicine and other areas of the life sciences can be characterized as control problems, with the goal of finding strategies to change a disease or otherwise undesirable state of a biological system into another, more desirable, state through an intervention, such as a...

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Bibliographic Details
Published in:BMC Syst Biol
Main Authors: Murrugarra, David, Veliz-Cuba, Alan, Aguilar, Boris, Laubenbacher, Reinhard
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035508/
https://ncbi.nlm.nih.gov/pubmed/27662842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0332-x
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