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The effect of inhibition of PP1 and TNFα signaling on pathogenesis of SARS coronavirus

BACKGROUND: The complex interplay between viral replication and host immune response during infection remains poorly understood. While many viruses are known to employ anti-immune strategies to facilitate their replication, highly pathogenic virus infections can also cause an excessive immune respon...

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Bibliografiske detaljer
Udgivet i:BMC Syst Biol
Main Authors: McDermott, Jason E., Mitchell, Hugh D., Gralinski, Lisa E., Eisfeld, Amie J., Josset, Laurence, Bankhead, Armand, Neumann, Gabriele, Tilton, Susan C., Schäfer, Alexandra, Li, Chengjun, Fan, Shufang, McWeeney, Shannon, Baric, Ralph S., Katze, Michael G., Waters, Katrina M.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035469/
https://ncbi.nlm.nih.gov/pubmed/27663205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-016-0336-6
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