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A Broad Set of Chromatin Factors Influences Splicing

Several studies propose an influence of chromatin on pre-mRNA splicing, but it is still unclear how widespread and how direct this phenomenon is. We find here that when assembled in vivo, the U2 snRNP co-purifies with a subset of chromatin-proteins, including histones and remodeling complexes like S...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Allemand, Eric, Myers, Michael P., Garcia-Bernardo, Jose, Harel-Bellan, Annick, Krainer, Adrian R., Muchardt, Christian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035054/
https://ncbi.nlm.nih.gov/pubmed/27662573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006318
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