Seasonal Malaria Chemoprevention with Sulphadoxine-Pyrimethamine and Amodiaquine Selects Pfdhfr-dhps Quintuple Mutant Genotype in Mali

BACKGROUND: Seasonal malaria chemoprevention (SMC) with sulphadoxine-pyrimethamine (SP) plus amodiaquine (AQ) is being scaled up in Sahelian countries of West Africa. However, the potential development of Plasmodium falciparum resistance to the respective component drugs is a major concern. METHODS:...

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Publicado no:PLoS One
Main Authors: Maiga, Hamma, Lasry, Estrella, Diarra, Modibo, Sagara, Issaka, Bamadio, Amadou, Traore, Aliou, Coumare, Samba, Bahonan, Soma, Sangare, Boubou, Dicko, Yeyia, Diallo, Nouhoum, Tembely, Aly, Traore, Djibril, Niangaly, Hamidou, Dao, François, Haidara, Aboubecrine, Dicko, Alassane, Doumbo, Ogobara K., Djimde, Abdoulaye A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035027/
https://ncbi.nlm.nih.gov/pubmed/27662368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162718
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