Population Pharmacokinetics and Pharmacodynamics of Lumefantrine in Young Ugandan Children Treated With Artemether-Lumefantrine for Uncomplicated Malaria

Background. The pharmacokinetics and pharmacodynamics of lumefantrine, a component of the most widely used treatment for malaria, artemether-lumefantrine, has not been adequately characterized in young children. Methods. Capillary whole-blood lumefantrine concentration and treatment outcomes were de...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Tchaparian, Eskouhie, Sambol, Nancy C., Arinaitwe, Emmanuel, McCormack, Shelley A., Bigira, Victor, Wanzira, Humphrey, Muhindo, Mary, Creek, Darren J., Sukumar, Nitin, Blessborn, Daniel, Tappero, Jordan W., Kakuru, Abel, Bergqvist, Yngve, Aweeka, Francesca T., Parikh, Sunil
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034953/
https://ncbi.nlm.nih.gov/pubmed/27471317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw338
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