Population Pharmacokinetics and Pharmacodynamics of Lumefantrine in Young Ugandan Children Treated With Artemether-Lumefantrine for Uncomplicated Malaria

Background. The pharmacokinetics and pharmacodynamics of lumefantrine, a component of the most widely used treatment for malaria, artemether-lumefantrine, has not been adequately characterized in young children. Methods. Capillary whole-blood lumefantrine concentration and treatment outcomes were de...

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Publicado en:J Infect Dis
Autores principales: Tchaparian, Eskouhie, Sambol, Nancy C., Arinaitwe, Emmanuel, McCormack, Shelley A., Bigira, Victor, Wanzira, Humphrey, Muhindo, Mary, Creek, Darren J., Sukumar, Nitin, Blessborn, Daniel, Tappero, Jordan W., Kakuru, Abel, Bergqvist, Yngve, Aweeka, Francesca T., Parikh, Sunil
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2016
Materias:
Major Articles and Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034953/
https://ncbi.nlm.nih.gov/pubmed/27471317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw338
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