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Development & automation of a novel [(18)F]F prosthetic group, 2-[(18)F]-fluoro-3-pyridinecarboxaldehyde, and its application to an amino(oxy)-functionalised Aβ peptide

2-[(18)F]-Fluoro-3-pyridinecarboxaldehyde ([(18)F]FPCA) is a novel, water-soluble prosthetic group. It's radiochemistry has been developed and fully-automated for application in chemoselective radiolabelling of amino(oxy)-derivatised RI-OR2-TAT peptide, (Aoa-k)-RI-OR2-TAT, using a GE TRACERlab...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Appl Radiat Isot
Egile Nagusiak: Morris, Olivia, Gregory, J., Kadirvel, M., Henderson, Fiona, Blykers, A., McMahon, Adam, Taylor, Mark, Allsop, David, Allan, Stuart, Grigg, J., Boutin, Herve, Prenant, Christian
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Pergamon Press 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034901/
https://ncbi.nlm.nih.gov/pubmed/27518217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apradiso.2016.07.023
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