Adipose tissue (P)RR regulates insulin sensitivity, fat mass and body weight

OBJECTIVE: We previously demonstrated that the handle-region peptide, a prorenin/renin receptor [(P)RR] blocker, reduces body weight and fat mass and may improve insulin sensitivity in high-fat fed mice. We hypothesized that knocking out the adipose tissue (P)RR gene would prevent weight gain and in...

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Bibliografske podrobnosti
izdano v:Mol Metab
Main Authors: Shamansurova, Zulaykho, Tan, Paul, Ahmed, Basma, Pepin, Emilie, Seda, Ondrej, Lavoie, Julie L.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2016
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034688/
https://ncbi.nlm.nih.gov/pubmed/27689008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.08.009
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