Andrographolide induces Nrf2 and heme oxygenase 1 in astrocytes by activating p38 MAPK and ERK

BACKGROUND: Andrographolide is the major labdane diterpenoid originally isolated from Andrographis paniculata and has been shown to have anti-inflammatory and antioxidative effects. However, there is a dearth of studies on the potential therapeutic utility of andrographolide in neuroinflammatory con...

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Publicado en:J Neuroinflammation
Autores principales: Wong, Siew Ying, Tan, Michelle G. K., Wong, Peter T. H., Herr, Deron R., Lai, Mitchell K. P.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034653/
https://ncbi.nlm.nih.gov/pubmed/27663973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-016-0723-3
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