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Virus-inspired polymer for efficient in vitro and in vivo gene delivery
Clinical translation of nucleic acids drugs has been stunted by limited delivery options. Here, we report a synthetic polymer designed to mimic viral mechanisms of delivery called VIPER (virus-inspired polymer for endosomal release). VIPER is composed of a polycation block for condensation of nuclei...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5034564/ https://ncbi.nlm.nih.gov/pubmed/27538359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201605958 |
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