A Generalized Gene-Regulatory Network Model of Stem Cell Differentiation for Predicting Lineage Specifiers

Identification of cell-fate determinants for directing stem cell differentiation remains a challenge. Moreover, little is known about how cell-fate determinants are regulated in functionally important subnetworks in large gene-regulatory networks (i.e., GRN motifs). Here we propose a model of stem c...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Okawa, Satoshi, Nicklas, Sarah, Zickenrott, Sascha, Schwamborn, Jens C., del Sol, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034562/
https://ncbi.nlm.nih.gov/pubmed/27546532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2016.07.014
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